Bicluster

Bicluster Motifs

Bicluster Genes

• Rv0078
• Rv0143c
• Rv0523c
• Rv0534c
• Rv0745
• Rv0855
• Rv1134
• Rv1238
• Rv1258c
• Rv1761c
• Rv1849
• Rv1858
• Rv1901
• Rv2118c
• Rv2288
• Rv2317
• Rv2514c
• Rv2522c
• Rv2541
• Rv2592c
• Rv2598
• Rv2910c
• Rv2912c
• Rv2946c
• Rv3026c
• Rv3239c
• Rv3439c
• Rv3554

Bicluster Conditions

• H37Rv.0.05..SDS.exposure.for.1h.rep.1
• H37Rv.0.05..SDS.exposure.for.1h.rep.4
• H37Rv.0.05..SDS.exposure.for.1h.rep.5
• MTB.strain.1254.Ctrl.vs.0.005.mM.DETA.NO.40min.rep.1.x
• MTB.strain.1254.Ctrl.vs.0.005.mM.DETA.NO.40min.rep.3.x
• MTB.strain.1254.Ctrl.vs.0.005.mM.DETA.NO.40min.rep.4.x
• MTB.strain.1254.Ctrl.vs.0.05.mM.DETA.NO.40min.rep.1.x
• MTB.strain.1254.Ctrl.vs.0.05.mM.DETA.NO.40min.rep.5.x
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.5min.rep.1
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.5min.rep.3
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.5min.rep.4
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.20min.rep.3
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.20min.rep.4
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.40min.rep.4.x
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.2hrs.rep.4
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.24hrs.rep.4
• MTB.strain.1254.Ctrl.vs.1.0.mM.DETA.NO.40min.rep.2.x
• MTB.strain.1254.Ctrl.vs.1.0.mM.DETA.NO.40min.rep.3.x
• MTB.strain.1254.Ctrl.vs.5.0.mM.DETA.NO.40min.rep.2.x
• MTB.strain.1254.Ctrl.vs.5.0.mM.DETA.NO.40min.rep.4.x
• CDC1551.Ctrl.vs.0.05.mM.DETA.NO.40.min.rep.1
• MTB1254.Day.0.vs.low.Oxygen.Day.4.rep.6
• H37Rv.vs..H37Rv.SDS.treated.rep.1
• H37Rv.vs..H37Rv.SDS.treated.rep.2
• H37Rv.vs..H37Rv.SDS.treated.rep.3
• H37Rv.vs..H37Rv.SDS.treated.rep.4
• H37Rv.vs..H37Rv.SDS.treated.rep.5
• H37Rv.vs..H37Rv.SDS.treated.rep.6
• H37Rv.0.2..Oxygen..2h..1
• H37Rv.0.2..Oxygen..2h..2
• H37Rv.0.2..Oxygen..2h..3
• H37Rv.0.2..Oxygen..2h..4
• H37Rv.Day.0.vs.low.Oxygen.Day.4.rep.6
• pH4.8vspH6.8..2h.B
• pH4.8vspH6.8..4h.
• pH4.8vspH6.8..4h.B
• pH4.8vspH6.8..4h.C
• pH4.8vspH6.8..6h.
• pH4.8vspH6.8..7h.
• pH5.2vspH6.8..5h.
• pH5.2vspH6.8..5.5h.
• pH5.2vspH6.8..10.5h.
• pH5.2vspH6.8..16h.
• pH5.6vspH6.8..2h.A
• pH5.6vspH6.8..4h.B
• pH5.6vspH6.8..5h.
• pH5.6vspH6.8..7h.
• pH5.6vspH6.8..11h.
• X0.02mM.GSNOvsDMSO..6h
• X0.1mM.GSNO.DMSO..3.5h
• X0.1mM.GSNOvsDMSO..4h
• X0.1mM.GSNO.DMSO..6h
• X0.1mM.GSNOvsDMSO..6h.
• X0.1mM.GSNOvsDMSO..6h.A
• Mtm.0.2ug.mL.vs.ctrl.8h.2.x
• X4mM.H2O2vsctrl..2h.
• X4mM.H2O2vsctrl..2h.A
• X4mM.H2O2.ctrl..2h...1
• X4mM.H2O2.ctrl..2h...2
• X4mM.H2O2.ctrl..4h...1
• X4mM.H2O2.ctrl..4h...2
• X4mM.H2O2vsctrl..4h.
• X4mM.H2O2vsctrl..4h.A
• H2O2.4mM.vs.ctrl.8h.1
• H37Rv.diamide.1h.rep.5
• H37Rv.diamide.1h.rep.6
• H37Rv.wild.type.control.vs.0.05..SDS.for.60.min.rep.1
• H37Rv.wild.type.control.vs.0.05..SDS.for.60.min.rep.2
• H37Rv.wild.type.control.vs.0.05..SDS.for.60.min.rep.3
• H37Rv.wild.type.control.vs.0.05..SDS.for.60.min.rep.4
• H37Rv.wild.type.control.vs.0.05..SDS.for.60.min.rep.5
• H37Rv.wild.type.control.vs.0.05..SDS.for.60.min.rep.6
• H37Rv.wild.type.control.vs.5mM.Diamide.for.60.min.rep.1
• H37Rv.wild.type.control.vs.5mM.Diamide.for.60.min.rep.2
• H37Rv.wild.type.control.vs.5mM.Diamide.for.60.min.rep.3
• H37Rv.wild.type.control.vs.5mM.Diamide.for.60.min.rep.4
• X20ug.ml.KCN.vs.DMSO.6hrs.x
• H37Rv.grown.in.7H9.vs.H37Rv.4hrs.after.infection.in.macrophages.rep.1
• H37Rv.grown.in.7H9.vs.H37Rv.4hrs.after.infection.in.macrophages.rep.2
• H37Rv.grown.in.7H9.vs.H37Rv.4hrs.after.infection.in.macrophages.rep.6
• H37Rv.grown.in.7H9.vs.H37Rv.24hrs.after.infection.in.macrophages.rep.1
• H37Rv.grown.in.7H9.vs.H37Rv.24hrs.after.infection.in.macrophages.rep.4
• CHP_25uM_1h_01
• CHP_25uM_24h_01
• MTB1254_SDS_90MIN_01
• MTB1254_SDS_90MIN_02
• MTB1254_SDS_90MIN_03
• MTB1254_SDS_90MIN_04
• SDS_60min_01
• Clinical.isolate.10514.01_Afri2.extra.vs.intracellular.in.activated.macrophages.rep.1
• Clinical.isolate.10514.01_Afri2.extra.vs.intracellular.in.activated.macrophages.rep.2
• Clinical.isolate.10517.01_Afri2.extra.vs.intracellular.in.activated.macrophages.rep.1
• Clinical.isolate.1797.03_EAI.extra.vs.intracellular.in.activated.macrophages.rep.1
• Clinical.isolate.2169.99_Uganda.extra.vs.intracellular.in.activated.macrophages.rep.1
• Clinical.isolate.2169.99_Uganda.extra.vs.intracellular.in.activated.macrophages.rep.2
• Clinical.isolate.2191.99_Uganda.extra.vs.intracellular.in.activated.macrophages.rep.1
• Clinical.isolate.2191.99_Uganda.extra.vs.intracellular.in.activated.macrophages.rep.2
• Clinical.isolate.2336.02_Haarlem.extra.vs.intracellular.in.activated.macrophages.rep.1
• Clinical.isolate.2336.02_Haarlem.extra.vs.intracellular.in.activated.macrophages.rep.2
• Clinical.isolate.947.01_EAI.extra.vs.intracellular.in.activated.macrophages.rep.1
• Clinical.isolate.947.01_EAI.extra.vs.intracellular.in.activated.macrophages.rep.2
• Clinical.isolate.9532.03_Haarlem.extra.vs.intracellular.in.activated.macrophages.rep.1
• CDC1551.extra.vs.intracellular.in.activated.macrophages.rep.1
• CDC1551.extra.vs.intracellular.in.activated.macrophages.rep.2
• Mtb.Erdman.strain.20.ppm.CO.rep.1
• Mtb.Erdman.strain.20.ppm.CO.rep.2
• Mtb.Erdman.strain.200.ppm.CO.rep.1
• Mtb.Erdman.strain.200.ppm.CO.rep.2
• Mtb.Erdman.strain.2000.ppm.CO.rep.1
• Mtb.Erdman.strain.2000.ppm.CO.rep.2
• Mtb.response.to.pH.5.5..6.replicates.
• Mtb.response.to.pH.6.5..6.replicates.
• BCG.2hr.phagosomal.profile
• BCG.24hr.phagosomal.profile
• M..tuberculosis.CDC1551.2hr.phagosome.expression.profile
• M..tuberculosis.CDC1551.24hr.phagosome.expression.profile
• MTB.in.Wild.type.macrophages.for.4hrs
• MTB.in.Wild.type.macrophages.for.24hrs
• MTB.in.Wild.type.macrophages...IFNg.for.24hrs
• MTB.in.Wild.type.macrophages...IFNg.for.48hrs
• MTB.strain.1254.Ctrl.vs.0.005.mM.DETA.NO.40min.rep.3.y
• MTB.strain.1254.Ctrl.vs.0.005.mM.DETA.NO.40min.rep.4.y
• MTB.strain.1254.Ctrl.vs.0.05.mM.DETA.NO.40min.rep.1.y
• MTB.strain.1254.Ctrl.vs.0.05.mM.DETA.NO.40min.rep.5.y
• MTB.strain.1254.Ctrl.vs.0.05.mM.DETA.NO.40min.rep.6.y
• MTB.strain.1254.Ctrl.vs.0.05.mM.DETA.NO.40min.rep.7.y
• MTB.strain.1254.Ctrl.vs.0.05.mM.H202.40min.rep.3
• MTB.strain.1254.Ctrl.vs.0.05.mM.H202.40min.rep.4
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.40min.rep.5
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.40min.rep.6
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.4hrs.rep.2
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.4hrs.rep.4
• MTB.strain.1254.Ctrl.vs.0.5.mM.H202.40min.rep.6
• MTB.strain.1254.Ctrl.vs.1.0.mM.DETA.NO.40min.rep.3.y
• MTB.strain.1254.Ctrl.vs.10.0.mM.H202.40min.rep.3
• MTB.strain.1254.Ctrl.vs.10.0.mM.H202.40min.rep.4
• MTB.strain.1254.Ctrl.vs.10.0.mM.H202.40min.rep.5
• MTB.strain.1254.Ctrl.vs.200.mM.H202.40min.rep.2
• MTB.strain.1254.Ctrl.vs.200.mM.H202.40min.rep.3
• MTB.strain.1254.Ctrl.vs.200.mM.H202.40min.rep.4
• MTB.strain.1254.Ctrl.vs.200.mM.H202.40min.rep.5
• MTB.strain.1254.Ctrl.vs.200.mM.H202.40min.rep.6
• MTB.strain.1254.Ctrl.vs.5.0.mM.DETA.NO.40min.rep.2.y
• MTB.strain.1254.Ctrl.vs.5.0.mM.DETA.NO.40min.rep.4.y
• MTB.strain.1254.Ctrl.vs.5.0.mM.H202.40min.rep.3
• MTB.strain.1254.Ctrl.vs.5.0.mM.H202.40min.rep.5
• MTB.strain.1254.Ctrl.vs.5.0.mM.H202.40min.rep.6
• MTB.strain.1254.Ctrl.vs.5.0.mM.H202.4hr.rep.1
• MTB.strain.1254.Ctrl.vs.5.0.mM.H202.4hr.rep.2
• MTB.strain.1254.Ctrl.vs.5.0.mM.H202.4hr.rep.3
• MTB.strain.1254.Ctrl.vs.50.0.mM.H202.40min.rep.3
• MTB.strain.1254.Ctrl.vs.50.0.mM.H202.40min.rep.6
• MTB.strain1254.vs.MTB.strain.1254.for.DETA.NO.exp.control.rep.1
• MTB.strain1254.vs.MTB.strain.1254.for.DETA.NO.exp.control.rep.3
• MTB.strain1254.vs.MTB.strain.1254.for.DETA.NO.exp.control.rep.4
• MTB.strain1254.vs.MTB.strain.1254.for.H2O2.exp.control.rep.1
• MTB.strain1254.vs.MTB.strain.1254.for.H2O2.exp.control.rep.5
• MTB.strain1254.vs.MTB.strain.1254.for.H2O2.exp.control.rep.6
• Russell_Lab_Spotted_Oligos_1.3..14.day.resting.macrophage.infection.Day.2..rep.1..Russell_Lab_Spotted_Oligos_1.3..
• Russell_Lab_Spotted_Oligos_1.5..14.day.resting.macrophage.infection.Day.4..rep.1..Russell_Lab_Spotted_Oligos_1.5..
• Russell_Lab_Spotted_Oligos_1.8..14.day.resting.macrophage.infection.Day.6..rep.2..Russell_Lab_Spotted_Oligos_1.8..
• Russell_Lab_Spotted_Oligos_1.16.14.day.resting.macrophage.infection.Day.14..rep.2..Russell_Lab_Spotted_Oligos_1.16.
• WT_140mM_NaCl_Rep3
• WT_140mM_NaCl_Rep4
• A00470_Q2_t60_diamide
• A00437_Q2_t60_diamide
• A00437_Q3_t90_diamide
• A00436_Q1_t30_diamide
• A00436_Q3_t90_diamide
• MTB.strain.1254.Ctrl.vs.0.5.mM.KCN.1hr.rep.1
• MTB.strain.1254.Ctrl.vs.0.5.mM.KCN.1hr.rep.2
• MTB.strain.1254.Ctrl.vs.0.5.mM.KCN.1hr.rep.3
• X1ug.mL..59vsDMSO..6h
• X1ug.mL..59vsDMSO..6hA
• X10ug.mL..59vsDMSO..6h
• X10ug.mL..59vsDMSO..6hA
• X1ug.mL..109vsDMSO..6h
• X10ug.mL..109vsDMSO..6h
• X10ug.mL..109vsDMSO..6hA
• X.109..0.1ug.mL..vs.DMSO..12h..GEO.acc.GSM28050.
• X.109..1ug.mL..vs.DMSO..12h..replicate.1..GEO.ac.GSM28051.
• X.109..10ug.mL..vs.DMSO..12h..replicate.1..GEO.acc..GSM28053.
• X.109..10ug.mL..DMSO..12h..replicate.2..GEO.acc..GSM28054.
• X1ug.mL..241vsDMSO..6h
• X1ug.mL..241vsDMSO..6hA
• X10ug.mL..241vsDMSO..6h
• X.241..0.1ug.mL..DMSO..12h..1..GEO.acc.GSM28046.
• X.241..1ug.mL..DMSO..12h..1
• X.241..10ug.mL..DMSO..12h..1
• X.241..10ug.mL..DMSO..12h..2
• X20ug.mL.Procept.6776vsDMSO..6h
• X20ug.mL.Procept6776vsDMSO..6h
• X30ug.mLProcept6776vsDMSO.6hA
• X5ug.mLProcept.6778vsDMSO.6h
• X5ug.mLProcept.6778vsDMSO.6hA
• X20ug.mLProcept6778vsDMSO.6h
• X20ug.mLProcept6778vsDMSO.6hA
• X20ug.mLProcept6778vsDMSO.6hB
• X10ug.mL.PA.1vsDMSO..6h
• X10ug.mL.PA.1vsDMSO..6hA
• X10ug.mL.PA.1vsDMSO..6hB
• X50ug.mL.PA.1vsDMSO..6h
• X10ug.mL.PA.21vsDMSO..6h
• X10ug.mL.PA.21vsDMSO..6hA
• X50ug.mL.PA.21vsDMSO..6h
• X0.4ug.mL.PA824.DMSO..6h..1
• X0.1mMGSNO.20ug.mLCPZvsDMSO.6hA
• X25ug.mLCPZ.0.1mMGSNO.DMSO..1
• X25ug.mLCPZ.0.1mMGSNO.DMSO..2
• X5ug.mL.CFZ.0.1mM.GSNO.DMSO..1
• X5ug.mL.CFZ.0.1mM.GSNO.DMSO..2
• X5ug.mLCFZ.0.1mMGSNOvsDMSO.A
• DIPED.5ug.mL.vs.DMSO.12h.2
• DIPED.10ug.mL.vs.DMSO.12h.2
• DIPED..50ug.mL..DMSO..12h
• DIPED.50ug.mL.vs.DMSO.12h.1
• DIPED.50ug.mL.vs.DMSO.12h.2
• DIPED..100ug.mL..DMSO..12h..1
• DIPED..100ug.mL..DMSO..12h..2
• DIPED..100ug.mL..DMSO..12h..3
• Mtm.0.2ug.mL.vs.ctrl.8h.1.y
• Mtm.0.2ug.mL.vs.ctrl.8h.2.y
• X0.1mg.mL.TriclosanvsEtOH..6h
• X0.1mg.mL.TriclosanvsEtOH..6hA
• X0.1mg.mLTriclosanvsEtOH.6hB
• X0.1mg.mLTriclosanvsEtOH.6hC
• X0.15mg.mL.TricvsEtOH..6h
• X10ug.mL.TriclosanvsDMSO..6h
• X10ug.mL.TriclosanvsDMSO..6hA
• X10ug.mL.TriclosanvsDMSO..6hB
• X50ug.mL.TriclosanvsEtOH..6h
• X50ug.mL.TriclosanvsEtOH..6hA
• X100ug.mL.TriclosanvsEtOH..6h
• X100ug.mL.TriclosanvsEtOH..6hA
• X24ug.mL.Econazole.DMSO..6h..1
• X10ug.mL.EMBvsDMSO..6h
• EMB..10ug.mL..DMSO..12h
• EMB.10ug.mL.vs.DMSO.12h.2
• EMB.10ug.mL.vs.DMSO.12h.3
• EMB.10ug.mL.vs.DMSO.12h.4
• X0.2mg.mL.AmpvsEtOH..6h
• X0.2mg.mL.AmpvsEtOH..6hA
• X0.2mg.mL.AmpvsEtOH..6hB
• X0.2mg.mL.AmpvsEtOH..6hC
• X25ug.mL.AntimycinvsDMSO..6h
• X50ug.mLAntimycinAvsDMSO..6h
• X50ug.mLAntimycinAvsDMSO..6hA
• X0.5ug.mL.CervsEtOH..6h
• X0.5ug.mL.CeruleninvsDMSO..6hA
• X0.5ug.mL.CeruleninvsDMSO..6hB
• X0.5ug.mL.CeruleninvsDMSO..6hC
• X20ug.mL.Cephalexin.Ctrl..6h..1
• X20ug.mL.Cephalexin.Ctrl..6h..2
• X100ug.mL.Ceph.DMSO..6h
• X100ug.mLCephalexinvsEtOH.6h
• X10ug.mLchlorpromazinevsctrl.6h
• X10ug.mLchlorpromazinevsctrl.6hA
• X20ug.mL.chlorprmz.DMSO..6h..2
• X25ug.mL.CPZvsDMSO..6h.A
• X60ug.mL.ChlorprovsEtOH..6h
• X50uM.CCCP.DMSO..6h..1
• X50uM.CCCP.DMSO..6h..2
• X2.5mM.Dinitrophenol.DMSO..6h
• X2mM.DTTvsDMSO..6h.A
• X12ug.mLEthionamidevsEtOH.6hA
• X40ug.mL.EtavsEtOH..6hA
• X0.2ug.mL.INH.EtOH..6h
• X0.4ug.mL.INHvsEtOH..6h
• X0.4ug.mL.INHvsEtOH..6hA
• X6ug.mL.MenadionevsDMSO..6h
• X10ug.mLmnd.Dubos.vsDMSO.6h
• X10ug.mLmdn.0.1mMGSNO.DMSO..2
• X10ug.mL.methoxatinvsDMSO..6h.A
• X50uM.NigericinvsDMSO..6h.A
• X0.2ug.mL.RifvsDMSO..6h
• X0.2ug.mL.RifvsDMSO..6hA
• Rif.5ug.mL.vsDMSO.2.5h
• Rif.5ug.mL.vsDMSO.2.5hA
• X0.1ug.mL.RifpvsEtOH..6h
• X0.5ug.mLRifapentinevsEtOH.6h
• X0.5ug.mLRifapentinevsEtOH.6hA
• X130ug.mL.TLMvsDMSO..6h
• X130ug.mL.TLMvsDMSO..6hA
• X0.2mg.mL.TLMvsEtOH..6h
• X0.2mg.mL.TLMvsEtOH..6hA
• X50ug.mL.Thioridazine.DMSO..6h
• X0.5uMValinomycinvsDMSO.6h
• X1uM.ValinomycinvsDMSO..6h.A
• X1uM.ValinomycinvsDMSO..6h.B
• X2mM.ZnSO4.DMSO..6h
• X0.2ug.ml.Isoniazid.vs.Ethanol.6hrs.rep.2
• X0.2ug.ml.Isoniazid.vs.Ethanol.6hrs.rep.3.x
• X130ug.ml.TLM.vs.DMSO.6hrs.rep.1
• X130ug.ml.TLM.vs.DMSO.6hrs.rep.2
• X0.5ug.mL.Cerulenin.vs.DMSO..6hrs.rep.3
• X0.5ug.mL.Cerulenin.vs.DMSO..6hrs.rep.4
• MTB1254.3524.1._INH_20MIN
• MTB1254.3524.2._INH_20MIN
• MTB1254_INH_20MIN
• X0.2mg.ml.Ampicillin.vs.Ethanol.6hrs
• X10ug.ml.Ethambutol.vs.DMSO.12hrs.3
• X5ug.ml.Rifampicin.vs.DMSO.2.5hrs
• CDC1551.ctrl.vs.40.ug.ml.Thioridazine.2hr.rep.2
• CDC1551.ctrl.vs.40.ug.ml.Thioridazine.6hr.rep.1
• CDC1551.ctrl.vs.40.ug.ml.Thioridazine.6hr.rep.2
• H37Rv.ctrl.vs.1ug.ml.Isoniazid.for.2hrs.rep.1
• H37Rv.ctrl.vs.1ug.ml.Isoniazid.for.2hrs.rep.3
• H37Rv.ctrl.vs.1ug.ml.Isoniazid.for.6hrs.rep.1
• H37Rv.ctrl.vs.1ug.ml.Isoniazid.for.6hrs.rep.2
• H37Rv.ctrl.vs.1ug.ml.Isoniazid.for.6hrs.rep.3
• H37Rv.KatG.null..ctrl.vs.1ug.ml.Isoniazid.for.2hrs.rep.3
• H37Rv.nutrient.starved..ctrl.vs.1ug.ml.Isoniazid.for.2hrs.rep.1
• H37Rv.O2.depleted..ctrl.vs.1ug.ml.Isoniazid.for.2hrs.rep.2
• H37Rv.mouse.hallow.fiber..ctrl.vs.25mg.kg.Isoniazid.3rd.dose.6hrs.rep.1
• H37Rv.mouse.hallow.fiber..ctrl.vs.25mg.kg.Isoniazid.3rd.dose.6hrs.rep.2
• H37Rv.Control.vs.400.ug.ml.vancomycin.for.1.hr.DS.rep.1
• H37Rv.Control.vs.400.ug.ml.vancomycin.for.4.hrs.DS.rep.1
• H37Rv.Control.vs.subinhibitory.conc..5.ug.ml..vancomycin.rep.2
• MTB.at.T0..biological.rep1
• MTB.at.T0..biological.rep2
• MTB.at.T0..biological.rep4
• MTB.at.T30..biological.rep1
• MTB.at.T30..biological.rep2
• MTB.at.T30..biological.rep3
• MTB.at.T60..biological.rep1
• MTB.at.T60..biological.rep2
• MTB.at.T180..biological.rep1
• MTB.at.T180..biological.rep2
• MTB.at.T180..biological.rep3
• MTB.at.T180..biological.rep4
• MTB.at.T360..biological.rep1
• MTB.at.T360..biological.rep2
• MTB.at.T360..biological.rep3
• MTB.at.T360..biological.rep4